Gene Therapy

Gene Therapy Is The Future Therapy!

At BIB, we are dedicated to providing high quality and on-time delivery for AAV material and services. Our highly experienced technical team and well-versed project management service will ensure your satisfaction at the completion of your project!

We Offer The Following Gene Therapy Services:

Adeno-Associated Virus (AAV) focused technology.

We will use advanced AAV-focused technology to help you with your business. We offer plasmid generation, scale-up, gene editing, AAV host cell screening, and AAV titer optimization.

Vector design, AAV production and analytical characterization.

We not only provide AAV-focused technology, but also provide Designing, Expression & Purification. We provide analytical testing services for AAV identity, quantification, and purity/impurity characterization by techniques such as by qPCR, ELISA, gel electrophoresis, and HPLC.

List of Gene Therapy Services

Vector Services
Design and Generation
Scale up production
Plasmids
Adenovirus
Retrovirus
Lentivirus
AAV

Virus Production
Transient expression
Stable expression
Mammalian/Insect CL
USP & DSP process development
Process Characterization
Scale up/down process development
cGMP manufacturing

Analytical Characterization Services
ELISA for titer
qPCR for titer
SDS-PAGE and DNA agarose gels
Dynamic light scattering (DLS)
ddPCR
HPLC
Cell-based infectivity and potency assays
Residual host cell protein and residual host cell DNA quantitation
Endotoxin quantitation

State-Of-The-Art Facilities

Boston Institute of Biotechnology provides full spectrum services which utilize next generation technologies, QbD and DoE methodologies. Our experienced scientists deliver the highest quality project results in a timely and efficient manner. We pride ourselves in achieving milestones for our customers with a focused mindset on commercialization.

Our Strengths

We provide Gene Therapy services with State-of-the-art facilities and high throughput technologies to support our clients with accurate and high standard of quality.

One stop service for pDNA, gene therapy and recombinant AdV/AAV vector production and vaccines from integrated production site.
Well established multi-expression suspension and adherent production platforms using HEK 293 & SF9 (and microbial fermentation platforms for pDNA production)
Efficient and robust AAV purification platform process QbD-driven DoE optimization system to enhance and stabilize AAV vector production
Robust and quantitative analytical assays for viral vectors
Experience with drugs in preclinical and throughout clinical development
First gene therapy CMC service provider in the world, and our clients include top multinational pharmaceutical companies

Don't Wait, Innovate

Alliance for People’s Health. United We Make Blockbusters

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